. 2020 Jun 16;10:929. doi: 10.3389/fonc.2020.00929

Table 2.

Glycopatterns changes between normal and BCa cells as determined by lectin microarray analysis.

Lectin	Binding structure	MCF7/MCF10A	MDA-MB-231/MCF10A	SK-BR-3/MCF10A
		Ratio
AAL	Terminal Fucα-1,6GlcNAc Fucα-1,3Galβ-1,4GlcNAc	2.76^NS	2.15^*	1.27^NS
ACA	Galβ1-3GalNAcα-Ser/Thr	3.07^***	3.00^**	2.60^***
BPL	Galβ1-3GalNAc	1.69^**	3.78^NS	4.03^*
BS-I	α-Gal, α-GalNAc	0.90^NS	1.00^NS	1.58^NS
ConA	Branched and terminal Man Terminal GlcNAc	0.43^***	0.32^*	0.59^**
DBA	GalNAcα-Ser/Thr GalNAcα1-3Gal	1.05^NS	1.02^NS	1.40^***
DSA	GlcNAc	0.73^NS	1.45^**	0.08^***
ECA	Galβ-1,4GlcNAc	0.31^**	0.44^***	0.45^***
EEL	Galα1-3(Fucα1-2)Gal	1.07^*	0.52^NS	0.61^*
GNA	Terminal α-1,3 Man	1.27^***	0.38^NS	0.88^NS
GSL-I	αGalNAc, αGal GalNAcα-Ser/Thr (Tn)	3.96^*	2.34^***	2.53^*
GSL-II	GlcNAc Galactosylated N-glycans	1.69^***	3.64^*	4.78^***
HHL	Non-substituted α-1,6 Man	0.89^**	0.48^NS	0.52^**
Jacalin	Galβ1-3GalNAcα-Ser/Thr (T) GalNAcα-Ser/Thr (Tn)	0.55^NS	0.97^***	0.61^**
LCA	Fucα-1,6GlcNAc (core)	0.53^***	0.22^***	0.43^***
LEL	Poly-LacNAc (GlcNAc)n	0.79^NS	0.73^NS	0.66^NS
LTL	sLe^x, Lex , Fucα-1,3GlcNAc (core)	0.57^NS	0.68^*	1.23^NS
MAL-I	Galβ-1,4GlcNAc	1.51^***	0.68^*	1.43^*
MAL-II	Siaα2-3Galβ1-4Glc(NAc)	0.54^**	0.21^*	0.31^**
MPL	αGalNAc	2.75^NS	1.28^*	0.83^NS
NPA	Non-substituted α-1,6Man	1.09^***	2.96^NS	3.31^**
PHA-E	Bisecting GlcNAc and bi-antennary N-glycans	0.68^**	0.42^*	0.51^**
PHA-E+L	Bisecting GlcNAc and bi-antennary N-glycans Tetra-antennary complex-type N-glycan	0.46^*	0.66^***	0.81^*
PNA	Galβ1-3GalNAcα-Ser/Thr (T)	1.14^*	1.43^*	0.63^**
PSA	Fucα-N-acetylchitobiose-Man	2.15^*	3.93^**	7.88^***
PTL-I	αGalNAc and Gal	0.95^***	2.18^NS	1.85^**
PTL-II	Gal	0.89^**	1.32^NS	1.42^*
PWM	GlcNAc	0.33^***	0.32^***	0.60^*
RCA120	Gal, GalNAc	1.42^**	0.29^*	0.57^**
SBA	Terminal GalNAc (especially GalNAcα1-3Gal)	0.91^NS	0.82^NS	1.42^*
SJA	Terminal GalNAc and Gal	0.11^*	2.01^*	2.12^*
SNA	Sia2-6Galβ1-4GlcNAc	7.04^***	2.69^***	2.65^**
STL	(GlcNAc)n	1.78^**	5.03^*	3.29^*
UEA-I	Fucα1-2Galβ1-4Glc(NAc)	2.45^*	3.42^***	5.13^***
VVA	GalNAc GalNAcα-Ser/Thr (Tn)	0.82^*	0.64^NS	0.94^NS
WFA	GalNAcα/β1-3/6Gal	0.28^*	1.48^***	1.40^*
WGA	Multivalent Sia (GlcNAc)n	0.70^**	0.36^NS	0.60^*

NS, not significant;

p < 0.05;

^**

p < 0.01; and

^***

p < 0.001.