Table 3.

Univariate analysis and multivariate analysis of patients.

	Univariate analysis			Multivariate analysis
	HR	95% CI	P-value	HR	95% CI	P-value
Sex
Female	Reference
Male	1.057	0.914–1.224	0.453
Age
<40	Reference			Reference
≥40	2.080	1.773–2.439	<2e−16	1.237	1.039–1.474	0.017
IDH_mutant_status
Mutant	Reference			Reference
Wild type	4.524	3.879–5.275	<2e−16	1.836	1.498–2.251	4.88e−09
WHO_grade
WHO II	Reference			Reference
WHO III	2.805	2.240–3.512	<2e−16	3.055	2.380–3.921	<2e−16
WHO IV	10.147	8.152–12.629	<2e−16	6.279	4.759–8.286	<2e−16
Radio_status
Yes	Reference
No	1.189	0.9858–1.435	0.0702
CHEMO_status
Yes	Reference
No	1.524	1.290–1.801	7.12e−07	0.691	0.576–0.830	7.36e−05
Radiosensitivity and XPO1 status
RR_XPO1_high	Reference			Reference
RR_XPO1_low	0.6473	0.5412–0.7742	1.91e−06	0.790	0.658–0.948	0.011
RS_XPO1_high	0.2483	0.1514–0.2311	<2e−16	0.583	0.451–0.754	3.75e−05
RS_XPO1_low	0.1871	0.1514–0.2311	<2e−16	0.433	0.340–0.552	1.39e−11