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. 2020 Jun 16;11:579. doi: 10.3389/fphys.2020.00579

TABLE 3.

Spearman’s correlation coefficient (ρ) between the hypoxia-adaptive gene expression and muscle histopathological indices.

Gene Histopathological index
FA CM
HIF1A (n = 35) ρ 0.2616 0.2392
P 0.129 0.1664
VEGFA (n = 35) ρ –0.4476 –0.584
P 0.007** 0.0002***

HIF1A, hypoxia inducible factor 1 subunit alpha; VEGFA, vascular endothelial growth factor A; FA, fibrotic area in the muscle; CM, circularity of myofibers. **P < 0.01, ***P < 0.001.