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. 2020 Jun 16;10:963. doi: 10.3389/fonc.2020.00963

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Copyright © 2020 Pan, Wang, Yang, Zhao, Zhai, Xu, Yang, Mao, Cheng, Xiao and Tan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cell cycle and DNA replication in LUSC based on LNM. (A) Cell cycle pathway and proteins that were enriched in the pathway. The protein quantifications are presented as mean ± SEM. (B) The diagram of DNA replication in cell cycle. Different protein complexes are represented in different colors. (C) The relationship MCM2 protein expression and LNM in tissue microarray (TMA) assay. (D) MCM2 expression and survival analysis in tissue microarray (TMA) assay. Chi-square test was adopted for the correlation analysis, and Kaplan–Meier plot (Log-rank test) was adopted to describe overall survival (OS) analysis.