Fig. 4.

(A) Activation in dmPFC and left TPJ was parametrically modulated by the advantageous timing regressor during the outcome screen (MNI coordinates in Supplementary Table S2). Brain images are presented in radiological convention. (B) Each subject’s dmPFC, lTPJ and dlPFC contrast parameter estimate and variance estimate were extracted and z-scored to enable activation comparison across subjects. We observed a dissociation in which positive activation in dmPFC correlated with advantageous timing, whereas activation in dlPFC did not. This pattern is the reverse of that found for opponent sensitivity in which the dlPFC (and not the dmPFC) was positively correlated with opponent sensitivity. The lTPJ was found to be correlated with both opponent sensitivity and advantageous timing. Bar height shows subject-level mean z-score parameter estimate; error bars denote standard error of the mean. See Materials and Methods for ROI definitions.