. 2020 Jun 16;11:506. doi: 10.3389/fphys.2020.00506

Table 2.

Analysis of deviance table (type II Wald Chi-square test) (***< 0.001; ** < 0.01; *<0.05; °< 0.1).

Parameter			Body mass		Sex		Caloric restriction		Interaction
			*Chisq*	*p-value*	*Chisq*	*p-value*	*Chisq*	*p-value*	*Chisq*	*p-value*
Creatinine (mg.ml⁻¹)			3.56	°	0.009	-	19.96	*******	0.002	-
Cortisol (ng.mgCreat. ⁻¹) (poisson)			153.71	***	0.07	-	299.47	*******	61.78	***
8-OHdG (ng.mgCreat. ⁻¹)			NS		13.26	*******	743.64	*******	0.01	-
(poisson)			Age effect : Chisq =7.41(**)
Thiols (μmol.mgProt. ⁻¹)			NS		0.55	-	4,01	*	6,69	**
GPx (U.mgProt. ⁻¹)			NS		2.76	°	0.02	-	7.80	**
17beta-Estradiol (pg.mgCreat. ⁻¹)			NS		5.11	*	30.28	***	1.52	-
Testosterone (ng.mgCreat. ⁻¹) (poisson)			9.63	**	10.71	**	0.99	-	18.23	***
Glycaemia (mg.dl⁻¹) (poisson)			NS		12.54	***	0.51	-	5.69	*
Body Mass (g)					7.55	**	140.24	***	2.37	-
Body Mass loss (g) (lm)			Initial body mass		0.052	-
			F-value= 10.9 **
Oxydative coupling rate (mlO₂.min⁻¹)			NS		3.83	°	0.43	-	6.23	*
Mitochondrial reserve capacity (mlO₂.min⁻¹)			NS		2.61	°	5.57	*	1.29	-
Mt/Nu DNA Ratio			NS		4.03	*	2,86	°	0.08	-
RER	NIGHT	Max	NS		0.01	-	11.10	***	6.77	**
		hMax	9.40		0.37	-	0.55	-	0.62	-
		Mean	NS		0.70	-	38.34	***	7.40	**
	DAY	Min	NS		1.98	-	0.31	-	1.01	-
		hMin	NS		1.81	-	10.18	**	0.89	-
VO2 (ml.kg⁻¹.h⁻¹)	NIGHT	Max	NS		0.34	-	0.33	-	0.01	-
		hMax	339.95	***	0.36	-	22.57	***	395.18	***
		Mean			3.13	°	0.42	-	5.25	*
	DAY	Min	NS		2.61	-	9.22	**	21.13	***
		hMin	NS		0.07	-	33.81	***	3.05	°
		Mean			0.003	-	0.013	-	7.37	**
EE (kcal.h⁻¹)	NIGHT	Max	NS		6.57	*	7.02	**	0.36	-
		hMax	NS		0.02	-	9.02	**	334.48	***
		Mean	NS		8.28	**	20.07	***	1.01	-
	DAY	Min	NS		9.03	**	22.32	***	8.4	**
		hMin	NS		8.19	**	62.64	***	15.73	***
		Mean	NS		1.69	-	18.65	***	4.93	*

Linear or generalized mixed effect models with random individual effect: Parameter ~ Body mass + Diet*Sex + (1|Indiv). Body mass was implemented in models when applicable. For non-Gaussian parameters, generalized mixed models with random effects were used when supported by the data sets (family “poisson” mentioned when applicable). A simple linear model (lm) was built to test the effect of sex on body mass loss. Models did not converge for a few parameters (T4 and GlcP); for non-parametric analysis, see Table 1.