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. 2020 Jun 16;14:617. doi: 10.3389/fnins.2020.00617

TABLE 3.

Results of phase randomization surrogate analyses for cardiorespiratory couplings between patients suffering from paranoid schizophrenia (SZO), healthy first-degree relatives (REL), and healthy control subjects (CON).

Index CON vs. SZO CON vs. REL SZO vs. REL CON
REL
SZO
Median [25–75] Median [25–75] Median [25–75]
Couplings NF *** n.s *** −2.0 −2.0 −1.8 −1.8 −1.9 −1.5 −0.9 −1.5 −0.2
ABBI → RESP *** * n.s 0.03 0.02 0.04 0.05 0.04 0.06 0.06 0.04 0.07
ARESP → BBI *** n.s *** 0.34 0.24 0.40 0.26 0.21 0.33 0.14 0.09 0.21
MuTEBBI → RESP ** n.s n.s 0.002 0.000 0.008 0.005 0.002 0.012 0.008 0.003 0.016
MuTERESP → BBI n.s n.s n.s 0.004 0.002 0.006 0.006 0.003 0.008 0.007 0.004 0.011

BB, beat-to-beat intervals; RESP, time intervals between consecutive breathing cycles; A, area from NSTPDC for identifying the coupling strength; MuTE, multivariate Transfer Entropy; p, univariate significance level: *<0.05, **<0.01, ***<0.004; n.s., not significant.