TABLE 2.
Regions of significant clusters with changed FA, MD, AD, and RD values in the tinnitus patients compared with the HCs according to the TBSS voxel-based analysis (FWE voxel p < 0.05).
| Cluster Index | Location of clusters | Volume (mm3) |
Mean DTI value |
p value | |
| Tinnitus | Control | ||||
| FA | |||||
| 1 | Body of CC | 141 | 4.2906 | 3.3838 | 0.002 |
| 2 | Genu of CC | 36 | 1.4034 | 1.2008 | 0.011 |
| 3 | LC | 24 | 0.6656 | 0.5560 | 0.003 |
| 4 | RC | 20 | 0.4924 | 0.3463 | 0.002 |
| 5 | RSLF | 11 | 0.5047 | 0.4761 | 0.01 |
| MD | |||||
| 1 | Body of CC | 10 | 0.0024 | 0.0026 | 0.022 |
| AD | |||||
| 1 | LC | 23 | 0.0028 | 0.0026 | 0.026 |
| 2 | LSLF | 8 | 0.0012 | 0.0011 | 0.005 |
| 3 | RICP | 6 | 0.0012 | 0.0011 | 0.004 |
| RD | |||||
| 1 | Body of CC | 60 | 0.0016 | 0.0024 | 0.019 |
| 2 | Genu of CC | 19 | 0.00069 | 0.00089 | 0.014 |
| 3 | RSLF | 10 | 0.00050 | 0.00054 | 0.001 |
FA, fractional anisotropy; MD, mean diffusivity; AD, axial diffusivity; RD, radial diffusivity; CC, corpus callosum; LC, left cingulum; RC, right cingulum; RSLF, right superior longitudinal fasciculus; LSLF, left superior longitudinal fasciculus; RICP, right interior cerebellar peduncle; FWE, family wise error; TBSS = tract-based spatial statistics.