Fig. 2.

Adaptive Immunity is Confounded by the AA Risperidone. Functionality of adaptive immune responses was assessed by measuring antibody responses following vaccination. To determine the ability to mount an immune response to antigen, RIS and _DVEH mice were administered Pneumovax23 (VAX) or vehicle (vVEH, sterile water). Antibody titers against pneumococcal antigen were significantly diminished in RIS-treated individuals (panel A). Individuals’ responder values (χ²) are shown, and black bars represent the group mean (panel B). No RIS-treated individuals were vaccine responders at the P ​< ​0.01 level, and only one was a responder at the P ​< ​0.05 level (red bars). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)