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. 2020 Jun 10;18(2):1803. doi: 10.18549/PharmPract.2020.2.1803

Table 3. Risk factors for erroneous and unintentional deviations from the guidelines in inpatients using dual antiplatelet therapy .

Risk factor n/N (%) in erroneous deviation from guidelines Univariate logistic regression
OR 95% CI p-value
Gender
Male 9/244 3.7 % Ref.
Female 2/167 1.2 % 0.32 0.07-1.48 0.14
Age 1.06 1.00-1.12 0.06
DAPT before admission
No 3/353 0.8 % Ref.
Yes 8/58 13.8 % 18.7 4.79-72.7 <0.0001
DAPT
ASA + clopidogrel 10/258 3.9 % Ref.
ASA + prasugrel 0/2 N/A 0.16 a 0.02-1.29 0.09
ASA + ticagrelor 1 / 151 0.7 %
Indication
Cardiovascular 6/213 2.8 % Ref.
Neurologic 4/193 2.1 % 0.73 0.20-2.63 0.63
Surgical 0/3 N/A 8.63 a 0.83-89.3 0.07
Multiple 1/2 50 %
a

the DAPT therapies ASA + prasugrel and ASA + ticagrelor and the indications surgical and multiple were analyzed as one group in the regression analyses due to low numbers.

DAPT: dual antiplatelet therapy; ASA: acetylsalicylic acid; N/A: not applicable; OR: odds ratio; CI: confidence interval