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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Mar 19;145(6):1629–1640.e4. doi: 10.1016/j.jaci.2020.01.051

FIG 2:

FIG 2:

Th2-associated gene expression in patients with active and inactive EoE (A) Expression of genes associated with eosinophils (CLC and CCR3) or mast cells (CPA3), Th2 activation (IL5, IL13, IL4, and TSLP), and eosinophil chemotaxis (CCL26) was measured and normalized by subtracting the Ct of GAPDH (ΔCt; active EoE n = 137, inactive EoE n = 100). Significance was assessed by Mann-Witney test. Dotted lines indicate limit of detection (B) Expression of genes in the EDP was averaged across active and inactive patients and differentially expressed genes were identified and annotated. Genes with ∣ΔΔCt∣ > 2 are indicated in blue if their expression was higher in inactive patients or in red if their expression was higher in active patients. * P < 0.05, *** P < 0.001. The data shown includes the cumulative results of all samples performed over 78 Custom TaqMan Gene Expression Array Cards. Experiments each supported the trends shown.