Skip to main content
. 2020 Jun 16;14:569. doi: 10.3389/fnins.2020.00569

FIGURE 5.

FIGURE 5

Persistent disruptions in synaptic and structural plasticity caused by long-term use of potentially addictive drugs. Studies are organized by cell type (columns) and type of disruption (rows), with symbols depicting the net change in plasticity and color depicting which drug was tested. Data from Bonci and Williams (1996), Kang et al. (1996, 1998), Robinson and Kolb (1997), Robinson and Kolb (2004), Badiani et al. (1999), Mansvelder and McGehee (2000), Dahchour and De Witte (2000), Uslaner et al. (2001), Brown and Kolb (2001), Robinson et al. (2002), Saal et al. (2003), Amantea et al. (2004), Hamilton and Kolb (2005), Nasif et al. (2005), Kolb et al. (2006), Kolb et al. (2018), Huang et al. (2007), Zhou et al. (2007), Van Den Oever et al. (2008), Kalivas et al. (2009), Niehaus et al. (2010), Russo et al. (2010), Bowers et al. (2010), Spiga et al. (2010), Levine et al. (2011), Dacher and Nugent (2011), Kroener et al. (2012), Lobo et al. (2013), Trifilieff and Martinez (2013), Mello et al. (2014), Peterson et al. (2015), Bloomfield et al. (2016), Creed et al. (2016), Ehlinger et al. (2016), Hearing et al. (2016), Morud et al. (2016), Friend L. et al., 2017), Langlois and Nugent (2017), Edwards et al. (2017), Spencer et al. (2018), You et al. (2018), Hwang and Lupica (2019), Kruse et al. (2019), McDevitt et al. (2019), Neuhofer et al. (2019), Pickel et al. (2019), and Ponzoni et al. (2019).