Table 1. Patient Characteristics.
| Variable | Population, No. (%) | |
|---|---|---|
| Intention to treat (N = 32) | Per protocol (n = 23) | |
| Men | 15 (47) | 10 (43) |
| Women | 17 (53) | 13 (57) |
| Age, mean (SD), y | 65.6 (5.6) | 66.0 (5.1) |
| Smoking | ||
| Current | 9 (28) | 4 (17) |
| Pack-years, mean (SD) | 37.6 (31.5) | 38.2 (31.5) |
| FEV1, % predicted, mean (SD) | 53.1 (13.2) | 53.7 (12.8) |
| GOLD grade 2 | 23 (72) | 16 (70) |
| Body mass index, mean (SD)a | 26.0 (4.5) | 25.3 (3.9) |
| Epworth sleepiness scale score, mean (SD) | 4.4 (3.3) | 4.6 (3.5) |
| Comorbidities | ||
| Cardiovascular disease including hypertension | 17 (53) | 12 (52) |
| Diabetes | 4 (13) | 3 (13) |
| Depression | 5 (16) | 3 (13) |
| Medication | ||
| Inhaled glucocorticosteroids | 5 (16) | 2 (9) |
| Inhaled β-adrenergics | 24 (75) | 17 (74) |
| Inhaled anticholinergics | 23 (72) | 18 (78) |
| Diuretics | 5 (16) | 2 (9) |
| Antihypertensive medication | 17 (53) | 12 (52) |
| Antidiabetics | 4 (13) | 3 (13) |
| Antidepressants | 5 (16) | 3 (13) |
Abbreviations: FEV1, forced expiratory volume in the first second of expiration; GOLD, Global Initiative for Obstructive Lung Disease.
a
Body mass index calculated as weight in kilograms divided by height in meters squared.