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. Author manuscript; available in PMC: 2020 Jun 23.
Published in final edited form as: J Invest Dermatol. 2018 Oct 31;139(4):868–877. doi: 10.1016/j.jid.2018.10.021

Figure 4. DOPG inhibits anti-microbial peptide DAMP-induced TLR activation in a TLR2 reporter cell line.

Figure 4.

(a) HEK-Blue-hTLR2 cells were incubated with or without S100A9 (10μg/mL) in the presence and absence of 100μg/mL DOPG or DOPC for 24 h or (b) with and without human β-defensin-2 (hBD2, 25μg/mL) in the presence and absence of 100μg/mL DOPG in the HEK-Blue detection medium for 18 h. SEAP activity was measured as absorbance at 620 nm. Values represent the means ± SEM from 3 separate experiments; ***p<0.001 versus the control; ††p<0.01, †††p<0.001 as indicated.