Table 4.
P10 | P25 | P50 | P75 | P90 | |
---|---|---|---|---|---|
HbA1c | |||||
GRS | 0.05b (0.00 −0.12) | 0.08b (0.04 −0.13) | 0.13b (0.09 −0.17) | 0.16b (0.10 −0.22) | 0.30b (0.19 −0.42) |
Degree: Less than HS | −0.03 (−0.02 to 0.09) | −0.05b (0.01–0.10) | 0.04 (−0.01 to 0.08) | 0.09b (0.00 −0.17) | 0.13 (−0.05 to 0.31) |
Degree: HS/GED | Reference | Reference | Reference | Reference | Reference |
Degree: College | −0.02 (−0.06 to 02.02) | −0.05b (−0.08 to 0.02) | −0.09b (−0.12 to −0.05) | −0.12b (−0.17 to −0.08) | −0.24b (−0.33 to −0.15) |
GRS*Less than HS | 0.09 (−0.03 to 0.22) | 0.12b (0.03 −0.21) | 0.11b (0.02 −0.19) | 0.18 (−0.01 to 0.37) | 0.26 (−0.04 to 0.56) |
GRS*College | −0.02 (−0.11 to 0.07) | −0.01b (−0.08 to 0.05) | −0.04b (−0.12 to 0.03) | −0.04 (−0.14 to 0.06) | −0.06 (−0.24 to 0.13) |
Constant | 5.60 | 5.86 | 6.57 | 7.70 | 8.94 |
n | 8207 | 8207 | 8207 | 8207 | 8207 |
BMI | |||||
GRS | 0.05b (0.25 −0.83) | 0.87b (0.62 −1.12) | 1.04b (0.73 −1.35) | 1.20b (0.84 −1.56) | 1.24b (0.62 −1.85) |
Degree: Less than HS | 0.51 (0.19 −0.84) | 0.18b (−0.12 to 0.48) | 0.25 (−0.13 to 0.64) | 0.64b (0.12 −1.17) | 1.25b (0.45 −2.06) |
Degree: HS/GED | Reference | Reference | Reference | Reference | Reference |
Degree: College | −0.43b (−0.69 to −0.16) | −1.01b (−1.22 to −0.80) | −1.34b (−1.68 to −1.01) | −1.39b (−1.78 to −1.00) | −1.46b (−2.01 to −0.91) |
GRS*Less than HS | 0.18 (−0.39 to 0.74) | 0.02 (−0.53 to 0.58) | 0.09 (−0.60 to 0.77) | 0.33 (−0.53 to 1.20) | 0.88 (−0.61 to 2.37) |
GRS*College | −0.09 (−0.56 to 0.37) | −0.36 (−0.76 to 0.05) | −0.17 (−0.67 to 0.33) | −0.15 (−0.76 to 0.46) | 0.09 (−1.01 to 1.19) |
Constant | 33.17 | 33.03 | 34.53 | 37.35 | 42.07 |
n | 8374 | 8374 | 8374 | 8374 | 8374 |
Models included age at time of outcome assessment as a continuous variable, a quadratic term for age, a binary variable for year of HbA1c outcome assessment (2006 vs. 2008), gender and six eigenvector variables reflecting differences in population distribution of risk.
p < 0.05.