Table 1.
Analyses of Factors Associated with Anorectal and Urogenital Mycoplasma genitalium Infection
| Anorectal Mycoplasma genitalium |
Urogenital Mycoplasma genitalium |
|||
|---|---|---|---|---|
| Unadjusted Risk Ratio (95% CI) | Adjusted Risk Ratio (95% CI) | Unadjusted Risk Ratio (95% CI) | Adjusted Risk Ratio (95% CI) | |
| Age | ||||
| < 22 years | Reference | Reference | Reference | Reference |
| 22-30 years | 0.79 (0.62-1.00) | 0.85 (0.67-1.07) | 0.98 (0.61-1.57) | 0.93 (0.56-1.54) |
| > 30 years | 0.68 (0.43-1.08) | 0.71 (0.44-1.12) | 0.78 (0.35-1.74) | 0.64 (0.28-1.46) |
| Gender Identity | ||||
| Cisgender Man | Reference | Reference | Reference | Reference |
| Transgender Woman | 1.05 (0.78-1.43) | 0.90 (0.66-1.28) | 0.43 (0.16-1.20) | 0.41 (0.16-1.06) |
| Other/Unknown | 0.80 (0.44-1.44) | 0.73 (0.42-1.28) | 0.81 (0.30-2.18) | 0.82 (0.34-2.02) |
| Sexual Orientation | ||||
| Gay/Homosexual | Reference | Reference | Reference | Reference |
| Bisexual† | 0.83 (0.66-1.05) | 0.90 (0.71-1.14) | 0.94 (0.58-1.54) | 0.71 (0.44-1.15) |
| Condom Use at Last Anal Sex | ||||
| Yes | Reference | Reference | Reference | Reference |
| No‡ | 0.92 (0.73-1.15) | 0.87 (0.69-1.09) | 0.94 (0.65-1.36) | 0.90 (0.61-1.35) |
| # of Partners for Receptive Anal Sex | ||||
| 0 | Reference | Reference | Reference | Reference |
| 1-2 | 1.34 (0.98-1.85) | 1.26 (0.92-1.74) | 1.30 (0.72-2.36) | 1.17 (0.67-2.06) |
| 3 or more | 1.72 (1.27-2.32) | 1.59 (1.16-2.18) | 1.04 (0.58-1.87) | 0.89 (0.50-1.59) |
| # of Partners for Insertive Anal Sex | ||||
| 0 | Reference | Reference | Reference | Reference |
| 1-2 | 0.93 (0.74-1.18) | 0.97 (0.77-1.23) | 2.51 (1.37-4.61) | 2.64 (1.40-4.96) |
| 3 or more | 0.82 (0.64-1.06) | 0.88 (0.68-1.56) | 2.96 (1.55-5.67) | 3.52 (1.77-6.98) |
| HIV Status | ||||
| Uninfected | Reference | Reference | Reference | Reference |
| Infected | 1.46 (1.08-1.98) | 1.37 (1.01-1.86) | 1.48 (0.81-2.69) | 1.84 (1.01-3.36) |
| Chlamydia Status* | ||||
| Uninfected | Reference | Reference | Reference | Reference |
| Infected | 1.40 (1.08-1.82) | 1.36 (1.04-1.76) | 1.32 (0.73-2.39) | 1.22 (0.68-2.21) |
| Gonorrhea Status* | ||||
| Uninfected | Reference | Reference | Reference | Reference |
| Infected | 1.18 (0.93-1.50) | 0.98 (0.78-1.24) | 2.35 (0.65-8.50) | 3.24 (0.70-14.92) |
Unadjusted and adjusted Poisson regression models with generalized estimating equations, clustered by participant, and robust error variance were used to calculate relative risk and 95% confidence intervals for factors associated with Mycoplasma genitalium infection at each anatomic site tested. Adjusted models included all factors listed in the table. Statistically significant associations (p≤0.05) are shown in bold.
The “bisexual” category of sexual orientation also includes two participants who reported “transgender” and one “queer.”
The “no” category of condom use at last anal sex with a male partner includes one participant who responded “don’t know” when asked about condom use.
Infection status for bacterial STIs was assessed at the same visit and the same anatomic site as the sample collection for Mycoplasma genitalium testing.