FIG 2.
Comparison of live C. trachomatis yields in genital tract tissues between mice with or without adaptive immunity following transcervical inoculation. C57BL/6J mice without (solid bars; n = 7) or with (open bars; Rag1−/−; n = 6) deficiency in adaptive immunity were infected with 5 × 106 IFU of C. trachomatis serovar D organisms via transcervical inoculation. All mice were monitored for live-organism recovery from the genital tract tissues, including vagina (Vag), cervix (Cex), uterus or uterine horn (UH), and oviduct or ovary (OV). The tissues were harvested on day 3 after transcervical inoculation. The number of live organisms recovered from each tissue is expressed as log10 IFU, and group means and standard deviations are shown. Data are from two independent experiments. P was >0.05 (Wilcoxon rank sum test) between C57BL/6J and Rag1−/− mice when IFU from any given tissue were compared.