FIG 3.

Comparison of live C. trachomatis yields between adaptive immunity-deficient mice with or without IL-2Rγc following transcervical inoculation. Mice deficient in Rag1 (Rag1^−/−; solid bars) or in both Rag2 and IL-2Rγc (Rag2^−/− & γc^−/−; open bars) were infected with 5 × 10⁶ IFU of C. trachomatis serovar D organisms via transcervical inoculation and then monitored for live-organism recovery from both vaginal swabs and genital tract tissues, including vagina (Vag), cervix (Cex), uterus or uterine horn (UH), and oviduct or ovary (OV). All swabs and tissues were harvested on day 3 after inoculation. The number of live organisms recovered from each swab or tissue is expressed as log₁₀ IFU, and group means and standard deviations are shown. n = 5 for each data point, and the data are from two independent experiments. *, P < 0.05 (Wilcoxon rank sum test).