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Evaluation of Th1 cytokines in the serum of WT and miR-155−/− mice. Serum levels of IFN-γ, TNF-α, IL-13, and IL-4 were measured from T. cruzi-infected WT and miR-155−/− mice. Significant decreases in IFN-γ, TNF-α, and IL-13 were observed in miR-155−/− mice. Data are shown from one representative experiment of three separate experiments and presented as a mean ± standard error of the mean (SEM). ***, P < 0.001; *, P < 0.05; ND, not detected.
