TABLE 1.
Cytokine levels in the lungs of Acinetobacter baumannii-infected C57BL/6 micea
| Time and group | Cytokine level (avg ± SEM) (pg/ml)b
|
|||||
|---|---|---|---|---|---|---|
| TNF-α | IL-1β | IL-4 | IL-6 | IL-10 | IL-12 | |
| 4 h | ||||||
| Untreated | 814.6 ± 52.1 | 241.5 ± 14.8 | 38.89 ± 3.7 | 3451.7 ± 40.6 | 129.4 ± 12.3 | 217.1 ± 4.3 |
| Clodronate | 407.8 ± 23.9† | 63.17 ± 5.8† | 51.37 ± 3.8 | 381.1 ± 11.2† | 126.6 ± 8.4 | 37.95 ± 9.2† |
| 24 h | ||||||
| Untreated | 541.8 ± 99.4 | 133.4 ± 20.1 | 80.28 ± 5.1 | 613.7 ± 61.4 | 82.89 ± 18.9 | 144.2 ± 9.5 |
| Clodronate | 208.3 ± 36.8† | 57.65 ± 3.2† | 93.73 ± 9.7 | 65.90 ± 25.9† | 82.69 ± 9.0 | 29.66 ± 7.5† |
a
n = 5 per group.
b
†, Lower cytokine levels (P < 0.05) than those of the untreated group.