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. Author manuscript; available in PMC: 2020 Jun 23.
Published in final edited form as: Clin Cancer Res. 2017 Jun 15;23(12):e62–e67. doi: 10.1158/1078-0432.CCR-17-0595

Table 4.

Suggested surveillance for rhabdoid tumors

Gene Organ at risk Type of mutation
Germline truncating Germline missense
SMARCB1 Brain MRI q 3 months to age 5 years No screening, generally no/very low risk
Abdomen Consider WBMRI to age 5 years, undetermined frequency. Ultrasound q 3 months No screening, generally no/very low riska
SMARCA4 Brain No data available, risks likely very low
Abdomen No data available, risk likely low to very low
Ovary No data available, abdominal ultrasound q 6 months may be justified, role, if any, of MRI unknown. Preventive oophorectomy may be justified outside of the pediatric age range

Abbreviations: q, every; WBMRI, whole-body MRI.

a

Schwannomas may result from missense mutations and may justify MRI.