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. 2020 Jun 16;11:886. doi: 10.3389/fphar.2020.00886

Table 1.

Relationship between ASD, BPSD and AD.

Diagnostic criteria for ASD in the Diagnostic and Statistical Manual of Mental Disorders (Rhodus et al., 2019) Similarities of ASD and BPSD (Rhodus et al., 2019) Common mechanisms of ASD and AD (Khan et al., 2016)

  • - Deficits in social communication and social interaction

  • - Restricted, repetitive patterns of behavior, interests, or activities including repetitive movements, use of objects, or speech

  • - Inflexibility in terms of routines

  • - Anxiety

  • - Depression

  • - Executive functioning deficits

  • - Communication deficits

  • - Inflammation

  • - Oxidative Stress

  • - Synapse formation

  • - Myelination

  • - Methylation

  • - Impaired cholinergic system