Table 2.
Comparison of secondary endpoints for the two groups at three time points after treatment
| CN (n = 149) | AT (n = 152) | P | |
|---|---|---|---|
| WOMAC scorea, median (Q1,Q3) | |||
| 46th day | 9 (5, 14) | 10 (7, 17) | 0.008 |
| 62nd day | 7 (4, 11) | 8 (5, 14.5) | 0.003 |
| 77th day | 6 (3, 11) | 11 (5, 16) | < 0.001 |
| Lysholm knee scoreb, median (Q1,Q3) | |||
| 46th day | 78 (69, 85) | 76 (66, 85) | 0.791 |
| 62nd day | 81 (75, 90) | 80 (70, 87) | 0.101 |
| 77th day | 81 (74, 93) | 80 (70, 88) | 0.030 |
| JOA scoreb, median (Q1,Q3) | |||
| 46 days | 90 (85, 95) | 90 (80, 95) | 0.648 |
| 62 days | 95 (85, 100) | 90 (80, 95) | 0.157 |
| 77 days | 95 (85, 100) | 90 (80, 95) | 0.013 |
| VAS scorea, median (Q1,Q3) | |||
| 46 days | 30 (17, 40) | 30 (20, 43) | 0.115 |
| 62 days | 21 (13, 35) | 25 (16, 37) | 0.162 |
| 77 days | 20 (8, 33) | 28 (10, 40) | 0.011 |
| SF-36 scoreb, median (Q1,Q3) | |||
| 46 days | 536.7 (454, 636) | 562.9 (464.6, 636) | 0.816 |
| 62 days | 599.3 (514.3, 664) | 590 (482.9, 651.6) | 0.294 |
| 77 days | 612.5 (518.2, 674) | 585.9 (487.3, 662) | 0.179 |
P represents the comparison between the two groups at the corresponding time points
WOMAC score Western Ontario and McMaster Osteoarthritis Index score, JOA score Japanese Orthopedic Association knee score, VAS visual analog scale, SF-36 the MOS 36-item short-form health survey
aDisease severity increases as scores rise
bDisease severity decreases as scores rise