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. 2020 Jun 22;15:133. doi: 10.1186/s11671-020-03348-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Total amount of oleanolic acid in PMO-G, PMO-H, oleanolic acid, and Tween 80 mixture dispersed in distilled water (Otw) and oleanolic acid and propylene glycol mixture dispersed in distilled water (OPG) permeated through skin and the amount of oleanolic acid in each formulation as a function of time. Amount of oleanolic acid remained in the skin after 24 h: 36.74 ± 0.72% (PMO-G), 56.22 ± 13.50% (PMO-H), 27.44 ± 7.02% (Otw), and 26.28 ± 5.42% (OPG). Amount of oleanolic acid permeated after 24 h: 21.39 ± 5.91% (PMO-G), 29.49 ± 4.00% (PMO-H), 13.66 ± 0.81% (Otw), and 5.90 ± 2.67% (OPG)