Table 1.
Lysine 2-hydroxyisobutyrulated sites identified in histones
| Protein accession | Position | Modified sequence | Histone description | Mass error [ppm] |
|---|---|---|---|---|
| Q6ZL42 | 121 | K(0.976)AGGSAK(0.024)AAAGD | H2A.2 | −0.42403 |
| Q6ZL43 | 14 | AIGAGAAK(1)K | H2A.1 | 0.15735 |
| Q94E96 | 137 | TAEK(1)AAAAGK | H2A.5 | −0.281 |
| Q94E96 | 11 | MDAAGAGAGGK(1)LK | H2A.5 | 0.17246 |
| Q94E96 | 133 | K(0.77)TAEK(0.23)AAAAGK | H2A.5 | −0.98919 |
| Q8S857 | 25 | AAADK(0.004)DK(0.996)DRK | H2A variant 2 | 2.6074 |
| Q8S857 | 13 | GLLAAK(1)TTAAK | H2A variant 2 | −1.4744 |
| Q84NJ4 | 14 | AIGSSAAK(1)K | H2A.3 | −0.70687 |
| Q9LGH8 | 67 | SVETYK(1)IYIFK | H2B.8 | 1.4873 |
| Q9LGH8 | 75 | VLK(1)QVHPDIGISSK | H2B.8 | 0.13234 |
| Q9LGH8 | 61 | K(1)SVETYK | H2B.8 | 0.61662 |
| Q9LGH8 | 108 | LAGESAK(1)LAR | H2B.8 | 0.77039 |
| Q9LGH8 | 26 | AEK(1)APAGK | H2B.8 | 0.76614 |
| Q9LGH8 | 137 | LVLPGELAK(1)HAVSEGTK | H2B.8 | −0.78709 |
| Q9LGH8 | 145 | HAVSEGTK(1)AVTK | H2B.8 | −0.72084 |
| Q9LGH8 | 72 | IYIFK(1)VLK | H2B.8 | −0.89643 |
| Q9LGH8 | 23 | KPAEEEPAAEK(1)AEK | H2B.8 | −0.20801 |
| Q943L2 | 18 | KPVEEK(1)AEK | H2B.11 | −0.032173 |
| Q9LGH4 | 108 | LAAEAAK(1)LAR | H2B.6 | 1.7336 |
| Q6F362 | 23 | KPAEEEPAAEK(1)APAAGK | H2B.9 | 0.78845 |
| Q7XUC9 | 92 | TVTAMDVVYALK(1)R | H4 | −0.57386 |
The number in parenthesis indicates the localization probability of Khib modification