Table 2.
Analysis of inflammatory markers using one-way ANOVA with Tukey’s multiple comparison test
| Inflammatory marker (normal reference range) | Control mean (std. dev) [range] {% in normal range} |
HIV negative-DVT mean (std. dev) [range] {% in normal range} |
HIV positive-DVT mean (std. dev) [range] {% in normal range} |
P value | Significant difference < 0.05 | ||
|---|---|---|---|---|---|---|---|
| Control vs. HIV negative-DVT | Control vs. HIV positive-DVT | HIV negative-DVT vs. HIV positive-DVT | |||||
|
WCC (M: 3.9–10.4 × 109/L F: 3.9–12.6 × 109/L) |
5.3 (0.9) [4.0–6.7] {80.0} |
8.3 (2.4) [4.6–13.8] {94.3} |
10.0 (7.8) [4.0–33.4] {83.3} |
0.028 | – | Yes | – |
|
CRP (< 10 mg/L) |
2.3 (2.4) [1–8] {100.0} |
60.9 (59.1) [1–193] {28.1} |
92.3 (76.6) [7–245] {8.3} |
0.003 | Yes | Yes | – |
| ESR (0–10 mm/h) |
5.0 (4.6) [1–15] {77.8} |
32.1 (36.6) [2–139] {46.9} |
46.4 (38.3) [9–116] {9.1} |
0.041 | – | Yes | – |
|
Fibrinogen (2–4 g/L) |
2.6 (0.7) [1.7–4.3] {70.0} |
3.6 (1.3) [1–7] {67.7} |
3.4 (1.2) [1.5–5.3] {63.6} |
0.086 | – | – | – |
|
Serum iron (M: 11.6–31.3 µmol/L F: 9.0–30.4 µmol/L) |
18.0 (9.0) [3–33] {90.0} |
8.7 (6.3) [2–29] {23.3} |
6.1 (3.6) [1.8–13] {10.0} |
0.0002 | Yes | Yes | – |
|
Transferrin (M: 2.2–3.7 g/L F: 2.5–3.8 g/L) |
3.0 (0.7) [2.3–4.5] {90.0} |
2.4 (0.7) [2.3–4.5] {50.0} |
1.9 (0.9) [0.6–3.2] {33.3} |
0.007 | – | Yes | |
|
Iron Saturation (M: 20–50% F: 15–50%) |
26.6 (15.2) [3–53] {70.0} |
17.7 (19.3) [3–97] {25.9} |
20.4 (28.3) [2–88] {12.5} |
0.505 | – | – | – |
|
Ferritin (µg/L) (M: 26–388 µg/L F: 8–252 µg/L) |
147.6 (131.3) [3–412] {80.0} |
187.3 (237.6) [1.3–1101] {77.8} |
240.4 (159.2) [7–487] {55.6} |
0.620 | – | – | – |
HIV human immunodeficiency virus, vs. versus, WCC white cell count, CRP C-reactive protein, ESR erythrocyte sedimentation rate