Table 3.
Analysis of haematological markers using one-way ANOVA with Tukey’s multiple comparison test
| Haematological marker (normal reference range) | Control mean (std. dev) [range] {% in normal range} |
HIV negative-DVT mean (std. dev) [range] {% in normal range} |
HIV positive-DVT mean (std. dev) [range] {% in normal range} |
P value | Significant difference < 0.05 | ||
|---|---|---|---|---|---|---|---|
| Control vs. HIV negative-DVT | Control vs. HIV positive-DVT | HIV negative-DVT vs. HIV positive-DVT | |||||
|
RCC (M: 4.2–5.9 × 1012/L F: 3.9–5.4 × 1012/L) |
5.3 (0.4) [4.5–5.8] {90.0} |
4.3 (0.9) [2.19–6.98] {65.7} |
3.7 (0.7) [2.5–5.0] 33.3} |
0.0003 | Yes | Yes | – |
|
Hb (M: 13.4–17.5 g/dL F: 11.6–16.4 g/dL) |
14.9 (1.5) [12.3–16.4] {100.0} |
12.7 (3.2) [4.6–18.5] {71.4} |
9.8 (3.3) [4.1–16.7] {25.0} |
0.0008 | – | Yes | Yes |
|
Hct (M: 0.4–0.5 L/L F: 0.3–0.5 L/L) |
0.5 (0.1) [0.4–0.5] {80.0} |
0.4 (0.1) [0.2–0.6] {77.1} |
0.3 (0.1) [0.2–0.5] {33.3} |
0.0004 | Yes | Yes | Yes |
|
MCV (M: 83.1–101.6fL F: 78.9–98.5fL) |
90.6 (9.4) [74–108.2] {80.0} |
89.8 (7.9) [57.7–102.8] {85.7} |
84.6 (11.2) [63.1–103.6] {75.0} |
0.183 | – | – | – |
|
MCH (M: 27.8–34.8 pg F: 26.1–33.5 pg) |
28.5 (2.8) [21.6–32.5] {70.0} |
29.1 (3.7) [15.3–36] {82.9} |
25.7 (5.1) [15.5–33.5] {66.7} |
0.047 | – | – | Yes |
|
MCHC (M: 33–35 g/dL F: 32.7–34.9 g/dL) |
31.5 (1.5) [29.2–33.8] {70.0} |
32.2 (2.2) [26.2–35.5] {45.7} |
30.3 (3.0) [23.3–33.3] {33.3} |
0.038 | – | – | Yes |
|
RCDW (M: 12.1–16.3% F: 12.4–17.3%) |
14.4 (1.6) [12.6–16.9] {90.0} |
15.0 (2.4) [11.9–22.1] {82.9} |
16.8 (3.1) [12.1–22.8] {58.3} |
0.040 | – | – | – |
|
Plt (M: 171–388 × 109/L F: 186–454 × 109/L) |
232.9 (35.8) [169–296] {90.0} |
287.2 (128.2) [36–7] {71.4} |
358.6 (182.5) [149–796] {58.3} |
0.087 | – | – | – |
|
MPV (M: 7.1–11.0 fL F: 7.3–11.3 fL) |
8.978 (1.2) [6.9–10.3] {88.9} |
8.8 (1.1) [7.1–11.4] {94.3} |
9.0 (0.9) [7.9–10.8] {100.0} |
0.779 | – | – | – |
Haem. haematological, HIV human immunodeficiency virus, vs. versus, RCC red cell count, Hb haemoglobin, Hct haematocrit, MCV mean corpuscular volume, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, RCDW red cell distribution width, Plt platelet count, MPV mean platelet volume