Table 1.
Baseline characteristics
| Parameter | Total |
|---|---|
| Sex (f/m) | 63/42 |
| Age | 79 (75, 82) |
| BMI | 27.7 (24.7, 30.8) |
| Cardiovascular Risk Factors | |
| Hypertension | 93 |
| Diabetes | 37 |
| Dyslipidaemia | 64 |
| Active smoking | 8 |
| Atrial fibrillation | 16 |
| Cardiovascular magnetic resonance | |
| LV EDVI (ml/m2) | 79 (65, 98) |
| LV ESVI (ml/m2) | 31 (18, 45) |
| LV EF (%) | 60.5 (47.4, 72.0) |
| LV Mass (g/m2) | 85 (69, 105) |
| LGE (g) | 26.1 (14.7, 45.8) |
| NYHA | |
| I, II, III, IV | 6, 35, 60, 4 |
| Laboratory Testing | |
| NTproBNP (pg/ml) | 1452 (608, 3916) |
| Creatinine (mg/dl) | 1.03 (0.86, 1.19) |
| eGFR (ml/min/1.73m2) | 60.0 (50.4, 75.3) |
| Echocardiography | |
| Peak aortic valve velocity (m/s) | 4.0 (3.6, 4.6) |
| Mean Gradient (mmHg) | 38 (29, 53) |
| Aortic valve area (cm2) | 0.8 (0.6, 0.9) |
Values are reported given as median and interquartile range or absolute numbers and associated percentage as appropriate.
LV left ventricular, EDVI/ESVI end-diastolic/systolic volume index, EF ejection fraction, eGFR estimated glomerular filtration rate; LGE late gadolinium enhancement; NYHA New York Heart Association; BMI body mass index