Table 5.
Flunixin and 5-hydroxyflunixin concentrations (ng/mL) in urine and oral fluids after intramuscular administration of flunixin meglumine at 2.2 mg/kg in finishing-age swine
| Group | Pig ID | Urine | Pen-Level Oral Fluids | ||
|---|---|---|---|---|---|
| Flunixin | 5-hydroxyflunixin | Flunixin | 5-hydroxyflunixin | ||
|
G1 (Day 1) |
260 | 9459.1 | 1295.0 | 168.6 | 21.0 |
| 261 | 3762.5 | 972.0 | |||
| 270 (C) | 231.4 | 16.5 | |||
| 273 | 3032.0 | 724.4 | |||
|
G2 (Day 4) |
262 | 60.3 | <LOQ | 16.8 | 10.9 |
| 264 | 22.7 | <LOQ | |||
| 269 | 35.5 | <LOQ | |||
| 274 (C) | 11.6 | <LOQ | |||
|
G3 (Day 8) |
258 | <LOQ | <LOQ | <LOQ | <LOQ |
| 266 (C) | <LOQ | NF | |||
| 268 | <LOQ | NF | |||
| 272 | <LOQ | NF | |||
|
G4 (Day 12) |
263 | NF | NF | 12.3 | 11.3 |
| 267 | <LOQ | NF | |||
| 271 | <LOQ | NF | |||
| 275 (C) | <LOQ | NF | |||
|
G5 (Day 16) |
257 | NF | NF | <LOQ | 10.6 |
| 259 | NF | NF | |||
| 265 (C) | NF | NF | |||
| 276 | NF | NF | |||
Note: Oral fluids were a group sample from all four pigs in the group at the day of necropsy. Concentrations that were below the level of quantification (LOQ) were designated “LOQ”. For this assay the LOQ was 5 ng/mL. If no flunixin or 5-hydroxyflunixin levels were detected, the sample was designated “NF”. Untreated, control pigs used to assess the potential for environmental contamination were designated (C)