IL-10+NT-3 delivery promotes axonal growth at 12 wpi. Axonal growth into bridge implants delivering (A) Blank (ctrl), (B) NT-3, (C) IL-10, or (D) IL-10+NT-3. Scale: 100 μm. (E) Axon density in bridge implants. “a, b, c” denotes p < 0.05 compared with Blank (ctrl), “d and e” denotes p < 0.05 compared with NT-3 condition, and “f” denotes p < 0.05 compared with IL-10 condition. Data are presented as mean ± SEM. n = 6 per group. Red identifies NF200. NF200, neurofilament 200; wpi, weeks postinjury.