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. 2020 Jun 16;26(11-12):672–682. doi: 10.1089/ten.tea.2019.0321

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Copyright 2020, Mary Ann Liebert, Inc., publishers

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FIG. 5. — IL-10+NT-3 delivery promotes oligodendrocyte myelination of regenerating axons at 12 wpi. Source of myelination from bridge implants delivering (A) Blank (ctrl), (B) NT-3, (C) IL-10, or (D) IL-10+NT-3. White arrows denote oligodendrocyte myelinated axons. Yellow arrows denote Schwann cell myelinated axons. Scale: 100 μm. (E) Density of oligodendrocyte myelinated axons. (F) Density of Schwann cell myelinated axons. “a, b, c” denotes p < 0.05 compared with Blank (ctrl), “d and e” denotes p < 0.05 compared with NT-3 condition, and “f” denotes p < 0.05 compared with IL-10 condition. Data are presented as mean ± SEM. n = 6 per group. Red identifies NF200, green identifies MBP, and blue identifies p-zero (P0).