Table 1.
Clinical characteristics of biopsy samples evaluated for EP4R
| Case | Age | Gender and neuter status | Breed | Case | Age | Gender and neuter status | Breed |
|---|---|---|---|---|---|---|---|
| SCC tumor tissues | Normal skin tissues | ||||||
| 1 | NR | FS | Labrador Retriever | 1 | NR | FS | Collie |
| 2 | 1 | MN | German Shepherd Dog | 2 | NR | MN | Yorkshire Terrier |
| 3 | 6 | FS | Mixed Breed | 3 | 3 | FS | Chihuahua |
| 4 | 10 | FS | Beagle | 4 | 3 | MN | Mixed Breed |
| 5 | 10 | FS | English Springer Spaniel | 5 | 5 | MI | Red Bone Hound |
| 6 | 10 | MN | Mixed Breed | 6 | 6 | MN | Boxer |
| 7 | 11 | FS | Mastiff | 7 | 9 | MN | Bichon Frise |
| 8 | 13 | MN | Mixed Breed | 8 | 9 | FS | Labrador Retriever |
| 9 | 13 | MN | Norwich Terrier | 9 | 12 | FS | German Shorthaired Pointer |
| AGASACA tumor tissues | Normal anal sac tissues | ||||||
| 1 | 6 | MI | Akita | 1 | 2 | FS | Mixed Breed |
| 2 | 8 | FS | Labrador Retriever | 2 | 3 | MN | Chow-Chow |
| 3 | 8 | MN | Mixed Breed | 3 | 4 | FS | Pitbull |
| 4 | 9 | MN | Brussels Griffon | 4 | 6 | MN | Mixed Breed |
| 5 | 9 | MN | Mixed Breed | 5 | 8 | FS | Mixed Breed |
| 6 | 10 | FS | Cavalier King Charles Spaniel | 6 | 9 | FS | Cocker Spaniel |
| 7 | 10 | FS | Labrador Retriever | 7 | 10 | FS | Mixed Breed |
| 8 | 11 | FS | Mixed Breed | 8 | 11 | FS | Mixed Breed |
| 9 | 14 | FS | Labrador Retriever | 9 | 12 | FS | Beagle |
| TCC tumor tissues | Normal bladder tissues | ||||||
| 1 | NR | MI | Beagle | 1 | 4 | MN | Goldendoodle |
| 2 | 4 | FS | Pitbull | 2 | 5 | FI | German Shorthair Pointer |
| 3 | 6 | FS | Golden Retriever | 3 | 5 | MN | Weimaraner |
| 4 | 9 | MN | Great Dane | 4 | 8 | MN | Yorkshire Terrier |
| 5 | 10 | MN | Sheltie | 5 | 9 | MN | Weimaraner |
| 6 | 11 | MN | Golden Retriever | 6 | 11 | MN | Australian Shepherd |
| 7 | 13 | MN | Mixed Breed | 7 | 12 | MN | Mixed Breed |
| 8 | 14 | FS | Chihuahua | 8 | 13 | FS | Cocker Spaniel |
| 9 | 14 | MN | West Highland White Terrier | 9 | 15 | FS | Toy Poodle |
AGASACA Apocrine Gland Anal Sac Adenocarcinoma, EP4R EP4 receptor, FI Female intact, FS Female spayed, MI Male intact, MN Male neutered, NR Not reported, SCC Squamous Cell Carcinoma, TCC Transitional Cell Carcinoma