Table 4.

Mean MDASI scores (SD)^a by sex and age groups, N = 2021

Symptoms	Age groups												Total
	18–29 years		30–39 years		40–49 years		50–59 years		60–69 years		70–80 years
	W	M	W	M	W	M	W	M	W	M	W	M	W	M
	(n = 64–65)	(n = 36)	(n = 115–116)	(n = 80–81)	(n = 222–227)	(n = 162–163)	(n = 251–257)	(n = 207–210)	(n = 242–248)	(n = 248–251)	(n = 182–188)	(n = 174–179)	(n = 1084–1101)	(n = 914–920)
Core items
Pain	1.69 (2.44)	1.17 (2.12)	1.69 (2.49)	1.64 (2.35)	2.22 (2.71)	1.90 (2.34)	2.39 (2.65)	1.97 (2.58)	2.53 (2.78)	2.04 (2.46)	2.21 (2.58)	2.10 (2.51)	2.24 (2.66)	1.94 (2.46)
Fatigue	3.45 (2.86)	2.36 (2.58)	2.87 (2.75)	1.96 (2.32)	2.53 (2.78)	1.94 (2.43)	2.57 (2.67)	1.87 (2.39)	2.03 (2.61)	1.90 (2.31)	1.78 (2.20)	1.80 (2.23)	2.39 (2.66)	1.90 (2.34)
Nausea	1.03 (2.03)	0.56 (1.59)	0.74 (1.62)	0.28 (0.97)	0.64 (1.70)	0.22 (0.83)	0.55 (1.61)	0.41 (1.51)	0.40 (1.40)	0.24 (0.84)	0.51 (1.37)	0.40 (1.28)	0.57 (1.58)	0.32 (1.16)
Disturbed sleep	2.47 (3.41)	1.92 (3.00)	1.70 (2.54)	1.57 (2.53)	1.87 (2.84)	1.26 (2.26)	2.05 (2.68)	1.56 (2.41)	1.83 (2.53)	1.44 (2.34)	1.95 (2.48)	1.23 (2.10)	1.93 (2.68)	1.42 (2.34)
Distress/feeling upset	2.55 (3.12)	1.72 (2.25)	2.00 (2.70)	1.84 (2.24)	1.63 (2.54)	1.09 (2.12)	1.58 (2.27)	1.39 (2.32)	1.58 (2.40)	1.18 (2.13)	1.54 (2.22)	1.09 (1.83)	1.68 (2.46)	1.27 (2.14)
Shortness of breath	0.88 (1.88)	0.58 (1.34)	0.64 (1.60)	0.99 (2.11)	0.66 (1.76)	0.72 (1.77)	0.67 (1.69)	0.85 (1.78)	1.20 (2.30)	1.19 (2.12)	1.45 (2.43)	1.36 (1.98)	0.93 (2.02)	1.02 (1.94)
Difficulty remembering	1.39 (2.64)	0.64 (1.48)	1.07 (2.12)	0.62 (1.72)	1.17 (2.24)	0.67 (1.52)	0.98 (1.83)	0.78 (1.57)	0.86 (1.65)	0.88 (1.50)	1.01 (1.63)	1.40 (2.11)	1.03 (1.94)	0.89 (1.69)
Lack of appetite	0.83 (1.92)	1.00 (1.97)	0.80 (2.07)	0.38 (1.34)	0.34 (1.12)	0.36 (1.22)	0.47 (1.35)	0.52 (1.60)	0.53 (1.62)	0.54 (1.49)	0.66 (1.61)	0.55 (1.34)	0.55 (1.55)	0.51 (1.46)
Drowsiness	2.66 (2.62)	2.17 (2.74)	2.26 (2.71)	1.89 (2.51)	1.96 (2.55)	1.84 (2.31)	1.98 (2.49)	1.75 (2.46)	1.57 (2.26)	1.73 (2.20)	1.63 (2.26)	1.56 (2.09)	1.89 (2.46)	1.75 (2.31)
Dry mouth	0.55 (1.23)	0.92 (2.03)	0.59 (1.72)	0.59 (1.74)	0.65 (1.86)	0.68 (1.69)	1.08 (2.22)	0.76 (1.80)	1.14 (2.22)	1.10 (2.18)	1.66 (2.54)	1.40 (2.32)	1.02 (2.14)	0.95 (2.02)
Sadness	2.15 (2.70)	1.67 (2.88)	1.84 (2.89)	1.16 (1.86)	1.48 (2.44)	1.03 (2.04)	1.34 (2.21)	1.19 (2.19)	1.29 (2.32)	1.02 (1.94)	1.22 (2.16)	1.14 (2.17)	1.44 (2.39)	1.12 (2.10)
Vomiting	0.58 (1.81)	0.17 (0.70)	0.30 (1.16)	0.31 (1.11)	0.26 (1.26)	0.11 (0.63)	0.26 (1.23)	0.23 (1.09)	0.19 (1.03)	0.26 (1.04)	0.35 (1.18)	0.25 (1.11)	0.28 (1.22)	0.22 (1.00)
Numbness/tingling	0.57 (1.37)	0.50 (1.40)	0.71 (1.67)	0.59 (1.57)	0.92 (2.21)	0.74 (1.76)	0.85 (1.85)	0.82 (1.88)	1.01 (2.11)	0.80 (1.89)	1.11 (2.07)	0.85 (1.76)	0.91 (1.99)	0.77 (1.79)
Interference items
General activity	2.17 (2.66)	1.44 (2.20)	1.75 (2.52)	1.65 (2.52)	1.94 (2.80)	1.65 (2.55)	1.83 (2.65)	1.54 (2.44)	1.95 (2.70)	1.49 (2.43)	1.78 (2.63)	1.39 (2.14)	1.88 (2.67)	1.52 (2.30)
Mood	2.69 (2.87)	2.08 (2.38)	2.30 (2.69)	1.73 (2.28)	1.96 (2.67)	1.77 (2.50)	1.56 (2.28)	1.25 (1.99)	1.38 (2.21)	1.15 (1.93)	1.34 (2.02)	1.20 (2.03)	1.71 (2.42)	1.38 (2.14)
Working	2.31 (2.92)	1.92 (2.68)	2.29 (3.00)	1.68 (2.38)	2.12 (2.96)	1.84 (2.70)	1.96 (2.75)	1.44 (2.43)	1.99 (2.78)	1.32 (2.30)	1.98 (2.74)	1.38 (2.20)	2.06 (2.83)	1.51 (2.41)
Relations with other people	2.20 (2.76)	1.89 (2.71)	1.89 (2.66)	1.41 (2.52)	1.61 (2.49)	1.46 (2.42)	1.30 (2.17)	1.00 (1.98)	1.38 (2.39)	0.96 (1.78)	1.04 (2.00)	1.02 (2.00)	1.45 (2.37)	1.15 (2.11)
Walking	0.45 (1.49)	0.36 (1.44)	0.34 (0.93)	0.67 (1.97)	0.77 (2.05)	0.61 (1.68)	1.05 (2.22)	0.86 (2.14)	1.51 (2.79)	1.02 (2.13)	1.79 (2.99)	1.32 (2.41)	1.11 (2.39)	0.91 (2.10)
Enjoyment of life	1.68 (2.50)	1.83 (2.71)	1.58 (2.56)	1.44 (2.42)	1.49 (2.52)	1.37 (2.32)	1.36 (2.22)	1.20 (2.25)	1.47 (2.65)	1.18 (2.16)	1.41 (2.31)	1.27 (2.38)	1.46 (2.45)	1.29 (2.30)

W women, M men

^a0 (“not present”) to 10 (“as bad as you can imagine”) NRS scale