TABLE 2: Plasmid sequence characteristics of K. pneumoniae isolates and comparative analysis with plasmid RSF1010-IncQ (accession number: M28829.1).
Isolates | K3R2 | K4R2 | K6R2 | K1E | IncQ (M28829.1) |
---|---|---|---|---|---|
Reference | This study | This study | This study | This study | Scholz et al. (1989) |
Size of the sequenced plasmid DNA | 27,508 bp | 27,325 bp | 59,776 bp | 84,800 bp | 8,684 bp |
GC | 57.95% | 58.13% | 55.35% | 53.84% | 61% |
CDS | 31 | 31 | 70 | 94 | 40 |
Inc | IncQ1 and NTP | IncQ1 and NTP | IncQ1 and NTP | IncQ1 and NTP | IncQ1 and NTP |
Resistance genes | bla KPC-2 | bla KPC-2 | bla KPC-2 | bla KPC-2 | str sul |
Mobility and replication | mobA | mobA | mobA | mobA | mobA |
Proteins | mobB | mobB | mobB | mobB | mobB |
mobC | mobC | mobC | mobC | mobC | |
repA | repA | repA | repA | repA | |
repB | repB | repB | repB | repB | |
repC | repC | repC | repC | repC | |
repF | repF | repF | repF | repF |
K: Klebsiella pneumoniae; R2: public hospital; E: private hospital; GC: guanine and cytosine; bp: base pairs; CDS: coding sequence; Inc: plasmid incompatibility group; KPC: Klebsiella pneumoniae carbapenemase; str: streptomycin; sul: sulfonamide; mob: mobility protein; rep: replication proteins; NTP: not typable.