TABLE 2: Distribution of TLR3 SNP genotypes in HTLV-infected cases and healthy controls.
| SNP | Model | Genotype | Genotype frequencies; n (%) | p a | OR (95% CI) | |
|---|---|---|---|---|---|---|
| HTLV-infected (100 cases) | Healthy (118 controls) | |||||
| rs3775296 | Codominant | CC | 70 (70.0%) | 60 (50.8%) | _ | ref |
| CA | 24 (24.0%) | 53 (44.9%) | 0.002 | 0.388 (0.215-0.702) | ||
| AA | 6 (6.0%) | 5 (4.2%) | 0.964 | 1.029 (0.299-3.540) | ||
| Dominant | CC | 70 (70.0%) | 60 (50.8%) | _ | ref | |
| CA + AA | 30 (30.0%) | 58 (49.2%) | 0.004 | 0.443 (0.253-0.776) | ||
| Recessive | CC + CA | 94 (94%) | 113 (95.8%) | _ | ref | |
| AA | 6 (6.0%) | 5 (4.2%) | 0.554 | 1.443 (0.427-4.876) | ||
| rs3775291 | Codominant | CC | 52 (52.0%) | 55 (46.6%) | _ | ref |
| CT | 43 (43.0%) | 56 (47.5%) | 0.458 | 0.812 (0.469-1.407) | ||
| TT | 5 (5.0%) | 7 (5.9%) | 0.649 | 0.755 (0.226-2.530) | ||
| Dominant | CC | 52 (52.0%) | 55 (46.6%) | _ | ref | |
| CT + TT | 48 (48.0%) | 63 (53.4%) | 0.428 | 0.806 (0.473-1.374) | ||
| Recessive | CC + CT | 95 (95%) | 111 (94.1%) | _ | ref | |
| TT | 5 (5.0%) | 7 (5.9%) | 0.764 | 0.835 (0.256-2.716) | ||
a: P values were calculated using χ 2 test; SNP: single nuclear polymorphism, OR: odds ratio, CI: confidence interval.