Table 1.

Angiogenic cargo of tumor cell-derived exosomes

Source cells	Angiognic cargo
Breast cancer	Annexin II, Heparanase, TGFβ, miR-126a
Bladder cancer	EDIL-3
Colorectal cancer	Plexin B2, Tetraspanin-8
Glioblastoma	Angiogenin, CXCR4, FGFa, IL-6, IL-8, MMP2, MMP9, TGFβ, TIMP-1, TIMP-2, VEGF
Lung cancer	Sortilin, miRNA-21, miRNA-23a, miRNA-210
Glioma	IGFBP1, IGFBP3, IGFBP5, IL-8, LOXL2, VEGF
Ovarian cancer	miRNA-21
Leukemia	Heparanase
Nasopharyngeal cancer	CD44v5, HAX-1, ICAM-1, MMP13
Malignant melanoma	VEGF, MMP2, IL-6
Multiple myeloma	Angiogenin, Heparanase, HGF, MMP9, Serpin E1, Serpin F1, VEGF