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. 2020 Jun 23;22:69. doi: 10.1186/s13058-020-01303-9

Table 3.

Association of PD-L1 staining with clinicopathologic factors in triple-negative patients without neoadjuvant chemotherapy

TC TCIC IC sTIL level
Factors Negative Positive Fisher Negative Positive Fisher Negative Positive Fisher Low High Fisher
N (%) N (%) P value N (%) N (%) P value N (%) N (%) P value N (%) N (%) P value
Age [N = 60] [N = 59] [N = 59] [N = 59]
 < 50 years 13 (87) 2 (13) 0.6339 11 (79) 3 (21) 0.5163 11 (79) 3 (21) 0.5163 6 (43) 8 (57) 0.5378
 ≥ 50 years 41 (91) 4 (9) 30 (67) 15 (33) 30 (67) 15 (33) 15 (33) 30 (67)
Race/ethnicity [N = 60] [N = 59] [N = 59] [N = 59]
 Black 13 (81) 3 (19) 0.3966 6 (38) 10 (63) 0.003 6 (38) 10 (63) 0.003 3 (19) 13 (81) 0.1211
 White+Latino 40 (93) 3 (7) 34 (81) 8 (19) 34 (81) 8 (19) 17 (40) 25 (60)
 Others 1 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0)
Histologic type [N = 59] [N = 58] [N = 58] [N = 58]
 IDC 53 (90) 6 (10) NA 40 (69) 18 (31) NA 40 (69) 18 (31) NA 20 (34) 38 (66) NA
 Metaplastic 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
Histologic grade [N = 59] [N = 58] [N = 58] [N = 58]
 2 11 (100) 0 (0) 0.582 8 (73) 3 (27) 1 8 (73) 3 (27) 1 5 (45) 6 (55) 0.4866
 3 42 (88) 6 (13) 32 (68) 15 (32) 32 (68) 15 (32) 15 (32) 32 (68)
sTIL level [N = 59] [N = 59] [N = 59] NA
 < 10% 21 (100) 0 (0) 0.0796 21 (100) 0 (0) 0.0001 21 (100) 0 (0) 0.0001
 ≥ 10% 32 (84) 6 (16) 20 (53) 18 (47) 20 (53) 18 (47)
Tumor size [N = 59] [N = 58] [N = 58] [N = 58]
 ≤ 2 cm 31 (97) 1 (3) 0.14 25 (78) 7 (22) 0.1144 25 (78) 7 (22) 0.1144 14 (44) 18 (56) 0.2326
 > 2 to 5 cm 19 (83) 4 (17) 14 (61) 9 (39) 14 (61) 9 (39) 6 (26) 17 (74)
 > 5 cm 3 (75) 1 (25) 1 (33) 2 (67) 1 (33) 2 (67) 0 (0) 3 (100)
pN [N = 59] [N = 58] [N = 58] [N = 58]
 (y)pN0 37 (90) 4 (10) 0.7838 30 (73) 11 (27) 0.559 30 (73) 11 (27) 0.559 15 (37) 26 (63) 0.4834
 (y)pN1 11 (85) 2 (15) 7 (54) 6 (46) 7 (54) 6 (46) 3 (23) 10 (77)
 (y)pN2 3 (100) 0 (0) 2 (67) 1 (33) 2 (67) 1 (33) 1 (33) 2 (67)
 (y)pN3 2 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0)
pM [N = 59] [N = 58] [N = 58] [N = 58]
 0 51 (89) 6 (11) 1 39 (68) 18 (32) 1 39 (68) 18 (32) 1 20 (35) 37 (65) 1
 1 2 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0) 0 (0) 1 (100)
pStage [N = 57] [N = 56] [N = 56] [N = 56]
 I 26 (93) 2 (7) 0.6264 22 (79) 6 (21) 0.3932 22 (79) 6 (21) 0.3932 12 (43) 16 (57) 0.437
 II 19 (86) 3 (14) 13 (59) 9 (41) 13 (59) 9 (41) 5 (23) 17 (77)
 III 4 (80) 1 (20) 3 (60) 2 (40) 3 (60) 2 (40) 2 (40) 3 (60)
 IV 2 (100) 0 (0) 1 (100) 0 (0) 1 (100) 0 (0) 0 (0) 1 (100)

IDC invasive ductal carcinoma, sTIL stromal tumor infiltrating lymphocytes