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. 2020 Jun 23;22:69. doi: 10.1186/s13058-020-01303-9

Table 6.

Summary of multivariate analysis in all patients with neoadjuvant chemotherapy showing the odds ratio (95% confidence interval) of variables significantly associated with PD-L1 scoring methods and sTIL level

Factor TC22C3 TCIC22C3 IC22C3 sTIL level
Race/ethnicity
 White+Latino vs. Black 0.10 (0.01, 0.76)a
 Others vs. Black NS
Histologic grade
 3 vs. 1 + 2 7.27 (1.94, 27.24)b 4.94 (1.31,18.73)a 4.38 (1.84, 10.45)c
sTIL level
 ≥ 10% vs. < 10% 6.10 (1.18, 41.16)a 6.71 (2.37, 18.99)c 4.39 (1.49, 12.85)b
Receptor group
 ER/PR pos vs. TNBC 0.10 (0.01, 0.63)b
 HER2 vs. TNBC NS
Tumor size
 > 2 to 5 cm vs. ≤2 cm NS
 > 5 cm vs. ≤2 cm 0.26 (0.09, 0.76)a

NS not significant

aP value < 0.05–0.01

bP value < 0.01–0.001

cP value < 0.001