Table 6.
Summary of multivariate analysis in all patients with neoadjuvant chemotherapy showing the odds ratio (95% confidence interval) of variables significantly associated with PD-L1 scoring methods and sTIL level
| Factor | TC22C3 | TCIC22C3 | IC22C3 | sTIL level |
|---|---|---|---|---|
| Race/ethnicity | ||||
| White+Latino vs. Black | 0.10 (0.01, 0.76)a | |||
| Others vs. Black | NS | |||
| Histologic grade | ||||
| 3 vs. 1 + 2 | 7.27 (1.94, 27.24)b | 4.94 (1.31,18.73)a | 4.38 (1.84, 10.45)c | |
| sTIL level | ||||
| ≥ 10% vs. < 10% | 6.10 (1.18, 41.16)a | 6.71 (2.37, 18.99)c | 4.39 (1.49, 12.85)b | |
| Receptor group | ||||
| ER/PR pos vs. TNBC | 0.10 (0.01, 0.63)b | |||
| HER2 vs. TNBC | NS | |||
| Tumor size | ||||
| > 2 to 5 cm vs. ≤2 cm | NS | |||
| > 5 cm vs. ≤2 cm | 0.26 (0.09, 0.76)a | |||
NS not significant
aP value < 0.05–0.01
bP value < 0.01–0.001
cP value < 0.001