Table 2.
Blood pressure managements | Interventions | Comments |
---|---|---|
Lifestyle modifications | Diet Exercise Stress reduction |
Required for all patients |
Pharmacological therapy | Antihypertensive medication •Diuretics - Loop - Thiazides •Calcium channel blockers •Beta-blockers •Renin-Angiotensin-Aldosterone System blockade - Angiotensin-converting enzyme inhibitors - ARB, angiotensin II receptor blockers - Mineralocorticoid receptor antagonists •Alpha1 antagonists •Alpha2 agonists |
Choice of medications depending on: •Patients' characteristics, •Tolerability •Medication side effect profiles |
Procedural or surgical interventions | Specific treatment modalities •Transplant renal artery angioplasty ± stenting •Continuous positive airway pressure (CPAP) •Bilateral native nephrectomy •Native renal denervation |
Etiologies of resistant hypertension •Transplant renal artery stenosis •Obstructive sleep apnea (OSA) •Failed native kidney •Sympathetic overactivity |