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. 2020 Jun 16;7:229. doi: 10.3389/fmed.2020.00229

Table 2.

Common interventions for post-kidney transplant hypertension.

Blood pressure managements Interventions Comments
Lifestyle modifications Diet
Exercise
Stress reduction
Required for all patients
Pharmacological therapy Antihypertensive medication
•Diuretics
- Loop
- Thiazides
•Calcium channel blockers
•Beta-blockers
•Renin-Angiotensin-Aldosterone System blockade
- Angiotensin-converting enzyme inhibitors
- ARB, angiotensin II receptor blockers
- Mineralocorticoid receptor antagonists
•Alpha1 antagonists
•Alpha2 agonists
Choice of medications depending on:
•Patients' characteristics,
•Tolerability
•Medication side effect profiles
Procedural or surgical interventions Specific treatment modalities
•Transplant renal artery angioplasty ± stenting
•Continuous positive airway pressure (CPAP)
•Bilateral native nephrectomy
•Native renal denervation
Etiologies of resistant hypertension
•Transplant renal artery stenosis
•Obstructive sleep apnea (OSA)
•Failed native kidney
•Sympathetic overactivity