Figure 3 |. Crystal structures of AaBioW and ligand complexes.

(a) Ribbon diagram of AaBioW illustrating the orientation of the P_II domain (in pink) and the Rossmann fold domain (in light blue). Secondary structural elements are demarcated. (b–d) Simulated annealing difference Fourier maps (F_o – F_c) of AaBioW complexes contoured to 2.5 σ (blue) showing the bound pimelate (b), AMP–CPP–Mg²⁺ (c), and AMP–CoA (d). The coordinates for ligand were omitted before map calculations. The coordinates of the complexes are superimposed and the ligands are shown in ball-and-stick representation.