Table 4.
Predictors of refeeding hypophosphatemiaa
| Hypophosphatemia (N = 98) | Normal Phosphorus (N = 123) | |||||
|---|---|---|---|---|---|---|
| Factors | Meanb | SDb | Meanb | SDb | t-testc | p value |
| Nadir BMI | 11.8 | 1.4 | 12.4 | 1.3 | 3.31 | 0.001 |
| Nadir %IBW | 56.7 | 6.3 | 58.5 | 5.5 | 2.21 | 0.03 |
| Admission Glucose (mmol/L) | 4.7 | 3.9–5.6 | 4.4 | 3.9–5.2 | 11,630 | 0.06 |
| Admission Albumin (g/L) | 36.8 | 6.8 | 38.0 | 6.3 | − 1.41 | 0.16 |
| Admission Prealbumin (g/L) | 0.19 | 0.08 | 0.21 | 0.06 | −1.87 | 0.06 |
| Admission WBC (109 L− 1) | 4.8 | 2.5 | 4.3 | 2.7 | −1.41 | 0.16 |
| Lean Mass (g)d | 27,597 | 4351 | 28,578 | 5702 | −0.92 | 0.36 |
| N | % | N | % | χ2 | pvalue | |
| Elevated admission AST (> 40 U/L) | 41 | 42 | 45 | 37 | 0.63 | 0.42 |
| Elevated admission ALT (> 45 U/L) | 49 | 50 | 54 | 44 | 0.81 | 0.37 |
BMI Body mass index, IBW Ideal body weight, WBC White blood cell, AST Aspartate aminotransferase test, ALT Alanine aminotransferase test
aHypophosphatemia defined as phosphorus < 0.87 mmol/L. 60 patients with hypophosphatemia on admission were excluded
bMedian (IQR) for not normally distributed variables
cMann-Whitney U test
dData for lean mass (g) was available for 38 patients with refeeding hypophosphatemia and 66 patients with normal phosphorus