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. 2020 Jun 23;9:27. doi: 10.1186/s40035-020-00198-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Volcano plot of analysed proteins (n = 70). Differences in protein levels between FTD patients and unaffected individuals displayed by log2(fold change) and significance level displayed as -log10(p). All proteins with significant differences (FDR adjusted p < 0.01) are displayed in purple. Proteins highlighted with gene names have a p < 0.001 or an absolute log2(fold change) > 0.5 (corresponding to a fold change < 0.7 or > 1.4). The five proteins with both a p < 0.001 and an absolute log2(fold change) > 0.5 are displayed in red