Fig. 4.

Patient group separations and clustering by VGF, TN-R and NF-M. a Separation of FTD patients and unaffected individuals by combining levels of VGF, TN-R and NF-M. NC (turquoise), PMC (yellow), PPA (black for contrast) and bvFTD (purple). b Hierarchical clustering of VGF, TN-R and NF-M levels similarly show that FTD patients and unaffected individuals primarily clustered separately. The four groups are indicated by the colored bar, NC (turquoise), PMC (yellow), PPA (white) and bvFTD (purple) and numbers have been added to each cluster for clarification. NC – Non-carriers, PMC – Presymptomatic mutation carriers, PPA – Primary progressive aphasia, bvFTD – Behavioural variant FTD