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. 2020 Jun 23;15(6):e0235174. doi: 10.1371/journal.pone.0235174

Table 1. Subject characteristics of pre- and postmenopausal women.

Premenopausal Postmenopausal p-value
N 38 31
Age, years (range) 49 (45–55) 55 (50–60) 0.001
Female sex hormones
Estradiol, pmol/l 140 (53–360) 57 (36–69) 0.0003
FSH, IU/l 13.3 (6.6–53.3) 67.8 (57.5–88.7) <0.0001
Body composition
Height, cm 170 (165–174) 167 (163–172) 0.38
Weight, kg 67.4 (60.2–70.6) 70 (61.2–78.7) 0.21
BMI 23.2 (21.4–24.7) 25.3 (21.9–27.5) 0.06
Fat mass, kg 20.5 (15.9–24.6) 24.3 (18.7–29.1) 0.04
Visceral fat mass, l 0.33 (0.21–0.46) 0.70 (0.34–1.24) 0.001
White blood cell counts
Leukocytes, x109cells/l 4.9 (4.2–6.0) 5.4 (4.6–6.3) 0.05
Total lymphocytes, x109cells/l 1.6 (1.4–1.9) 1.8 (1.5–2.2) 0.01
Monocytes, x109cells/l 0.4 (0.3–0.5) 0.5 (0.4–0.5) 0.02
Neutrophils, x109cells/l 2.6 (1.8–3.2) 2.8 (2.4–3.5) 0.08
Neutrophil/lymphocyte ratio, AU 1.7 (1.0–2.7) 1.4 (1.2–2.2) 0.92

Data presented as median (interquartile range) unless otherwise stated. N, number of subjects. FSH, follicle stimulating hormone. AU, arbitrary units. Variables in pre-and postmenopausal women were compared using an unpaired t-test. If normal distribution could not be achieved through logarithmic transformation comparisons were performed using a Mann-Whitney U test.