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. 2020 Jun 23;15(6):e0235161. doi: 10.1371/journal.pone.0235161

Table 2. Multiple logistic regression analyses—independent variables with p ≤ 0.20 in simple logistic regression were included.

Adjusted OR (95% CI)
Vascular complicationsa
Age (years)
    18–39 1
    40–59 6.54 (4.31, 9.92)
    ≥60 15.98 (10.30, 24.81)
Sex
    Male 1
    Female 0.65 (0.54, 0.79)
Occupation
    Never worked/retired 1
    Non-manual worker 0.81 (0.63, 1.04)
    Manual worker 1.06 (0.83, 1.34)
Marital status
    Married 1
    Single/divorced/widowed 1.48 (1.12, 1.96)
T2DM duration (years)
    ≤1 1
    >1–5 0.91 (0.60, 1.37)
    >5–10 1.47 (0.96, 2.23)
    >10 2.75 (1.81, 4.17)
Blood glucose level (HbA1c, %)
    <7% 1
    ≥7% 1.13 (0.89, 1.43)
    Unknown 0.61 (0.36, 1.02)
T2DM therapeutic regimen
    Lifestyle modificationi only 1
    Lifestyle modificationi + OADii 1.20 (0.89, 1.63)
    Lifestyle modificationi + insuliniii 1.34 (0.94, 1.91)
    Lifestyle modificationi + OADii + insuliniii 1.54 (1.15, 2.06)
Hypertension
    No 1
    Yes 1.50 (1.25, 1.81)
Hyperlipidaemia
    No 1
    Yes 0.91 (0.74, 1.13)
    Unknown 0.28 (0.11, 0.69)
Microvascular complicationsb
Age (years)
    18–39 1
    40–59 3.50 (2.26, 5.42)
    ≥60 5.04 (3.20, 7.96)
Education
    University/college 1
    Class 7–12 1.46 (1.11, 1.92)
    Class 1–6 1.63 (1.22, 2.17)
    No qualification 1.95 (1.41, 2.71)
Occupation
    Never worked/retired 1
    Non-manual worker 0.81 (0.64, 1.02)
    Manual worker 1.07 (0.87, 1.30)
Marital status
    Married 1
    Single/divorced/widowed 1.41 (1.12, 1.77)
T2DM duration (years)
    ≤1 1
    >1–5 1.16 (0.76, 1.76)
    >5–10 2.22 (1.46, 3.38)
    >10 3.70 (2.45, 5.57)
Blood glucose level (HbA1c, %)
    <7% 1
    ≥7% 1.11 (0.90, 1.36)
Unknown 0.67 (0.41, 1.08)
T2DM therapeutic regimen
    Lifestyle modificationi only 1
    Lifestyle modificationi + OADii 1.15 (0.87, 1.51)
    Lifestyle modificationi + insuliniii 1.42 (1.03, 1.95)
    Lifestyle modificationi + OADii + insuliniii 1.57 (1.21, 2.03)
Hypertension
    No 1
    Yes 1.28 (1.09, 1.52)
Hyperlipidaemia
    No 1
    Yes 0.98 (0.82, 1.17)
    Unknown 0.09 (0.03, 0.32)
Macrovascular complicationsc
Age (years)
    18–39 1
    40–59 8.47 (4.40, 16.29)
    ≥60 24.14 (12.57, 46.34)
Sex
    Male 1
    Female 0.71 (0.60, 0.84)
Smoking (current status)
    No 1
    Yes 1.37 (1.11, 1.70)
T2DM duration (in years)
    ≤1 1
    >1–5 0.76 (0.50, 1.15)
    >5–10 1.07 (0.71, 1.61)
    >10 1.47 (0.99, 2.20)
Blood glucose level (HbA1c, %)
    <7% 1
    ≥7% 1.14 (0.94, 1.38)
    Unknown 0.71 (0.44, 1.15)
Hypertension
    No 1
    Yes 1.47 (1.24, 1.74)

BMI, body mass index; CI, confidence interval; HbA1c, glycated haemoglobin; OAD, oral antidiabetic drug; OR, odds ratio; T2DM, type 2 diabetes mellitus.

aVariables included age, sex, education, occupation, marital status, residence, health insurance, alcohol drinking, T2DM duration, blood glucose level (HbA1c), T2DM therapeutic regimen, BMI, hypertension, and hyperlipidaemia.

bVariables included age, education, occupation, marital status, health insurance, smoking, T2DM duration, blood glucose level (HbA1c), T2DM therapeutic regimen, BMI, hypertension, and hyperlipidaemia.

cVariables included age, sex, education, occupation, residence, health insurance, smoking, alcohol drinking, T2DM duration, blood glucose level (HbA1c), T2DM therapeutic regimen, BMI, hypertension, and hyperlipidaemia.

idiet and physical activity.

iimetformin, acarbose, sulfonylureas, meglitinides, and/or thiazolidinediones.

iiilong-term insulin, intermediate insulin, rapid-acting insulin, and/or premix insulin.