Table 2.
Genotype MTBDRsl Ver 2.0 hybridization pattern observed in resistant isolates
| Hybridization band(s) observed | Rifampicin resistant (N) | Isoniazid mono-resistant (N) | Total | ||
|---|---|---|---|---|---|
| Newly diagnosed | Follow-up | Newly diagnosed | Follow-up | ||
| gyrA gene | |||||
| gyrA MUT1 | 25 | 27 | 2 | 4 | 58 |
| WT/gyrA MUT1 | 1 | 3 | 0 | 0 | 4 |
| WT1-, WT2- | 1 | 0 | 1 | 2 | |
| gyrA MUT2 | 4 | 7 | 0 | 0 | 11 |
| WT2- | 1 | 2 | 1 | 0 | 4 |
| WT/gyrA MUT2 | 1 | 4 | 0 | 0 | 5 |
| gyrA MUT3A | 13 | 15 | 2 | 0 | 30 |
| gyrA MUT3B | 9 | 12 | 0 | 1 | 22 |
| gyrA MUT3A and MUT3C | 0 | 2 | 0 | 0 | 2 |
| gyrA MUT3B and MUT3D | 0 | 2 | 0 | 0 | 2 |
| gyrA MUT3C | 39 | 87 | 7 | 6 | 139 |
| WT/gyrA MUT3A | 0 | 1 | 0 | 0 | 1 |
| WT/gyrA MUT3B | 0 | 1 | 0 | 1 | 2 |
| WT/gyrA MUT3C | 6 | 6 | 1 | 2 | 15 |
| gyrA MUT3D | 0 | 3 | 0 | 0 | 3 |
| gyrA MUT3B and MUT3C | 1 | 1 | 0 | 0 | 2 |
| gyrA MUT1 and MUT3A | 1 | 1 | 2 | ||
| WT3- | 2 | 17 | 1 | 0 | 20 |
| rrs gene | |||||
| rrs MUT1 | 3 | 27 | 1 | 1 | 32 |
| WT/rrs MUT1 | 2 | 9 | 0 | 1 | 12 |
| WT/rrs MUT2 | 2 | 2 | 0 | 0 | 4 |
| eis gene | |||||
| eis MUT1 | 1 | 7 | 0 | 0 | 8 |
| eis WT2 absent | 4 | 10 | 1 | 0 | 15 |
| WT/eis MUT1 | 0 | 1 | 0 | 1 | 2 |