Table 1. Commonly utilized repositories and biobanks for distribution of human iPSC models.
The iPSC collections listed are broadly available for research use following material transfer agreement and minimal investigator cost. Cell lines available include patient-derived iPSC models of various common and rare diseases, as well as age-matched controls, isogenic controls, and gene-edited iPSCs.
| Repository, cell line bank, or vendor | Human iPSC lines available |
|---|---|
| Allen Institute iPSC Cell Collection (via Coriell Insitute) | >30 fluorescently labeled iPSC lines derived from WTC parental iPSC line |
| ATCC | ~20 iPSC lines derived from unaffected individuals of various ethnicities |
| California Institute for Regenerative Medicine (CIRM) iPSC bank | >1500 iPSC lines, including >100 from ASD spectrum, proband, and unaffected siblings |
| European Bank for induced pluripotent Stem Cells (EBiSC) | >800 iPSC lines, including both controls and models of ataxias, Dravet syndrome, ALS |
| New York Stem Cell Foundation | Variety of control and patient-derived iPSC lines, including CLN3 Batten disease |
| NIGMS iPSC Collection (via Coriell Insitute) | >50 iPSC lines, including CLN2 Batten disease, Friedreich Ataxia, NPC1, and SMA |
| NINDS and NIH CRM iPSC Collection | >130 iPSC lines, including controls, reporter lines and models of SMA and Huntington’s disease |
| Riken BRC | >450 rare disease-derived iPSC lines, including Spinocerebellar degeneration, neuropathies |
| Simons Foundation Autism Research Initiative | >100 iPSC lines from ASD subjects, including Phelan-McDermid syndrome |
| WiCell | >1400 iPSC lines, including Rett syndrome, FXS, and SMA models |