Table 62-1.
Mechanisms of Immune Protection by the Adaptive Immune Response
| Cellular | Humoral |
|---|---|
| Lysis of infected cells | Reduction of initial microbial inoculum |
| Elimination of source of production of viruses and intracellular pathogens | Direct neutralization of pathogen |
| Elaboration of antimicrobial cytokines | Complement-mediated lysis of bacteria and parasites |
| Recruitment of innate immune effector cells | Lysis of infected cells through antibody-dependent cell-mediated cytotoxicity |
| Induction of long-term immune memory | Recruitment of inflammatory cells through complement-dependent mechanisms |
| Elaboration of chemokines to recruit inflammatory responses | Generation of secretory IgA to facilitate mucosal elimination of pathogens |
| Secretion of proteins that block pathogen receptors |