Table 2.
Clinical and Laboratory Characteristics of Patients with KOA in the Present Study
| Variables | Total | MetS vs nMetS | ||||
|---|---|---|---|---|---|---|
| MetS-OA | nMetS-OA | P value | ||||
| N, (%) | 108 | 57 (52.78%) | 51 (47.22%) | – | ||
| Age (years) | 64.65 ± 8.32 | 64.11 ± 7.79 | 65.25 ± 8.92 | 0.476 | ||
| Height (m) | 1.61 ± 0.07 | 1.61 ± 0.06 | 1.60 ± 0.07 | 0.206 | ||
| Weight (kg) | 68.57 ± 10.12 | 72.79 ± 9.52 | 63.86 ± 8.66 | <0.001 | ||
| BMI (kg/m2) | 26.52 ± 3.30 | 27.86 ± 2.99 | 25.02 ± 2.98 | <0.001 | ||
| WC (cm) | 90.51 ±10.83 | 96.07 ± 9.25 | 84.30 ± 8.98 | <0.001 | ||
| Hypertension, n (%) | 60 (55.56%) | 42 (73.68%) | 18 (35.29%) | <0.001 | ||
| FBG (mg/dl) | 98.47 ± 23.48 | 105.31 ± 15.99 | 90.82 ± 27.94 | <0.001 | ||
| TG (mg/dl) | 197.90 ± 130.21 | 262.26 ± 146.64 | 125.96 ± 46.91 | <0.001 | ||
| HDL-C (mg/dl) | 51.76 ± 10.57 | 47.59 ± 11.04 | 56.43 ± 7.77 | <0.001 | ||
| CRP (mg/mL) | 5.03 ± 2.76 | 5.99 ± 3.01 | 3.95 ± 1.97 | <0.001 | ||
| ESR (mm/h) | 17.57 ± 15.32 | 21.00 ± 16.16 | 13.73 ± 13.46 | 0.013 | ||
| Plasma leptin (ng/mL) | 16.09 ± 9.90 | 20.49 ± 10.23 | 11.17 ± 6.75 | <0.001 | ||
| SF leptin (ng/mL) | 11.73 ± 8.10 | 15.29 ± 8.72 | 7.76 ± 4.97 | <0.001 | ||
| Plasma adiponectin (ng/mL) | 8.61 ± 2.00 | 9.99 ± 0.61 | 6.65 ± 1.61 | <0.001 | ||
| SF adiponectin (ng/mL) | 2.11 ± 1.80 | 2.71 ± 1.89 | 1.24 ± 1.22 | <0.001 | ||
| Plasma resistin (ng/mL) | 7.67 ± 4.61 | 9.63 ± 4.65 | 4.07 ± 0.75 | <0.001 | ||
| SF resistin (ng/mL) | 2.96 ± 1.72 | 3.08 ± 1.89 | 2.73 ± 1.35 | 0.318 | ||
| METS-IR | 40.29 ± 6.98 | 44.57 ± 5.68 | 35.49 ± 4.87 | <0.001 | ||
Note: Data are mean ± SD unless otherwise indicated.
Abbreviations: KOA, knee osteoarthritis; MetS-OA, osteoarthritis patients with metabolic syndrome; nMetS-OA, osteoarthritis patients without metabolic syndrome; BMI, body mass index; WC, waist circumference; FBG, fasting blood glucose; TG, triglycerides; HDL-C, high-density lipoprotein-cholesterol; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; SF, synovial fluid; METS-IR, metabolic score for insulin resistance.