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. 2020 Jun 21;10(6):e035933. doi: 10.1136/bmjopen-2019-035933

Table 1.

Demographic characteristics and comparison of comorbid disorders between the diabetes mellitus and control groups

Diabetes mellitus (n=239 854) Control (n=239 854) P value
n (%) n (%)
Age (years), mean±SD 55.08±14.86 55.08±14.86 >0.999
Age (years)
 20–49 91 232 (38.04%) 91 232 (38.04%) >0.999
 50–64 85 616 (35.70%) 85 616 (35.70%)
 ≥65 63 006 (26.27%) 63 006 (26.27%)
Gender
 Male 133 638 (55.72%) 133 638 (55.72%) >0.999
 Female 106 216 (44.28%) 106 216 (44.28%)
Baseline comorbidities
 Hypertension 74 296 (30.98%) 26 099 (10.88%) <0.0001
 Hyperlipidaemia 24 892 (10.38%) 6091 (2.54%) <0.0001
 Chronic renal disease 5972 (2.49%) 2235 (0.93%) <0.0001
 Keratoconjunctivitis sicca 517 (0.22%) 388 (0.16%) <0.0001
RCE 1236 (0.52%) 884 (0.37%) <0.0001
Overall follow-up time, years
 Median (Q1–Q3) 9.27 (8.43–10.12) 9.33 (8.51–10.15) <0.0001
Time to RCE, years
 Median (Q1–Q3) 4.08 (1.63–6.72) 4.15 (1.82–6.60) 0.6503

Demographic characteristics and comorbid disorders were compared between the diabetes mellitus and control groups by using McNemar’s test. The mean age was estimated using paired t-test, and the median of follow-up time and time to RCE were calculated with Wilcoxon’s signed rank test.

RCE, recurrent corneal erosion.